The heavy-tail distribution function for gene expression in bacteria and tumor tissues
نویسنده
چکیده
Based on data on gene expression profiles from microarrays for E. Coli and tumor tissues, I show the existence of heavy tails in the gene expression distribution functions, related to a set of strongly overand under-expressed genes. The tails are heavier – i.e. the fraction of genes and the expression levels are much higher (lower) – in tumors than in bacteria, presumably due to epigenetic factors. Different tissue tumors show remarkably similar tails, indicating a kind of universality in cancer phenomena.
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تاریخ انتشار 2017